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Activated from the antibiotic rifampicin and many plant metabolites, such as hyperforin, guggulipid, colupulone, and isoflavones. Reaction to distinct ligands is species-certain. Activated by Obviously transpiring steroids, for example pregnenolone and progesterone. Binds to some response aspect during the promoters on the CYP3A4 and ABCB1/MDR1 gen